amatuer spot colour question

is printing spot colour tints of the same pantone colour workable? that is, laying down a percentage (be it 100%, 10% or anything inbetween) of a specified spot colour, and adding tints of various strengths of the same spot colour over top of the base percentage. if so, is there an advisable tint percentages to work with?

and, is it foolish to use transparency ie multiply, opacity percentages etc with spot colours - be they the same pantone or multiple pantones?

thanks in advance.